Biology
🔒 Log in to trackCell, organelles and genetics
🔒 Log in to trackThe cell is the basic unit of life. Each organelle inside it has one job and one nickname, such as mitochondria as the powerhouse. Cells divide by mitosis for growth and by meiosis to make gametes. Genetics adds a few names and numbers: Mendel, Watson and Crick, and 46 human chromosomes.
Who found what about the cell
Each scientist has one signature fact. Match the fact to the name.
| Discovery | Scientist |
|---|---|
| Cell (in cork, 1665) | Robert Hooke |
| First living cells, bacteria (single-lens microscope) | Antonie van Leeuwenhoek |
| Nucleus (1831) | Robert Brown |
| Cell theory | Schleiden (plants) and Schwann (animals) |
| 'Omnis cellula e cellula': new cells come from existing cells | Rudolf Virchow |
Watch: Hooke saw dead cork walls and named the cell. Leeuwenhoek was the first to see living cells.
Cell organelles
An organelle is a small working part inside the cell.
| Organelle | Job or nickname |
|---|---|
| Mitochondria | Powerhouse of the cell. Aerobic respiration, ATP. Has its own DNA |
| Ribosomes | Protein synthesis. No membrane |
| Lysosomes | 'Suicide bags'. Hold digestive enzymes |
| Golgi apparatus | Packaging and secretion |
| Endoplasmic reticulum | Transport. Rough ER (with ribosomes) makes proteins. Smooth ER makes lipids |
| Chloroplast | Photosynthesis. Plants only. Has its own DNA |
| Nucleus | Control centre. Holds the chromosomes (DNA) |
| Vacuole | Storage. Large in plant cells |
| Cell wall | Plants (cellulose) and fungi (chitin). Absent in animal cells |
Tip: Four nicknames answer most questions: mitochondria = power, lysosome = suicide bag, ribosome = protein, Golgi = packing.
Cell types and cell records
- Prokaryotes (bacteria, blue-green algae) have no nuclear membrane and no membrane-bound organelles.
- Eukaryotes have a true nucleus.
- Largest cell: ostrich egg. Longest cell: nerve cell (neuron). Smallest cell: Mycoplasma (PPLO).
- The ovum is the largest human cell.
- Mature mammalian RBCs have no nucleus. An RBC lives about 120 days. The spleen removes worn-out RBCs.
Cell division
| Mitosis | Meiosis | |
|---|---|---|
| Purpose | Body growth and repair | Makes gametes |
| Cells formed | 2 identical cells | 4 cells |
| Chromosome number | Stays the same | Halved |
Take a human cell. Mitosis keeps 46. Meiosis gives 23 in each gamete.
Genetics basics
- Gregor Mendel is the father of genetics. He worked on the garden pea (Pisum sativum).
- His laws are dominance, segregation and independent assortment.
- DNA double helix: Watson and Crick (1953), using X-ray data of Rosalind Franklin and Maurice Wilkins.
- DNA bases are A, T, G, C. RNA has uracil in place of thymine.
Human chromosomes and inheritance
Body cells hold 46 chromosomes (23 pairs). That is 22 pairs of autosomes plus 1 pair of sex chromosomes. Gametes hold 23.
Rule: The father decides the sex of the child. XX is female. XY is male.
- Haemophilia and colour blindness are X-linked. They are more common in males.
- Down syndrome is an extra chromosome 21 (trisomy 21).
Theories and names to know
- Hugo de Vries: mutation theory.
- Darwin: natural selection (On the Origin of Species, 1859).
- Lamarck: inheritance of acquired characters.
- Har Gobind Khorana: Nobel Prize 1968 for work on the genetic code.
Question types you will see
Each type: how to recognise it, the method step by step, and one question to try.
Cell theory and discoverers
Words like 'who discovered the cell / nucleus / living cells', 'cell theory', 'omnis cellula e cellula', or a year (1665, 1831).
Read the noun: cell, living cell, nucleus or theory.
Match it to its one scientist from the table.
Use the year to break ties: 1665 Hooke, 1831 Brown.
Each scientist has exactly one signature fact.
The cell theory was proposed by which pair of scientists?
Show solutionHide solution
Theory means Schleiden (plants) and Schwann (animals).
Hooke only named the cell.
Virchow added that cells come from cells.
Schleiden and Schwann
Organelle and its function or nickname
'Powerhouse of the cell', 'suicide bags', 'which organelle makes protein', 'which organelle has its own DNA'.
Find the nickname or job in the question.
Recall the pair from the organelle table.
For own DNA, choose mitochondria or chloroplast.
The question is always one nickname or one job.
Which organelle is called the 'suicide bag' of the cell?
Show solutionHide solution
Suicide bag means it digests the cell itself.
Lysosomes hold digestive enzymes.
Lysosome
Prokaryote vs eukaryote, plant vs animal cell
'Which is a prokaryote', 'no true nucleus', 'cell wall is made of', 'absent in animal cells'.
Bacteria and blue-green algae are prokaryotes. Everything else is eukaryote.
Cell wall, chloroplast and large vacuole mark plant cells.
For 'absent in animal cells', pick cell wall or chloroplast.
Prokaryotes lack a nuclear membrane and membrane-bound organelles.
The cell wall of a plant cell is made of what?
Show solutionHide solution
Plants use cellulose in the wall.
Fungi use chitin.
Cellulose
Cell division and chromosome numbers
'Chromosomes in a human body cell', 'chromosomes in a gamete', 'mitosis vs meiosis', 'which division keeps the number the same'.
Body cell: 46. Gamete: 23.
Growth and repair means mitosis: the number stays.
Gamete formation means meiosis: the number halves.
Meiosis halves the number so fertilisation can restore it.
A human gamete contains how many chromosomes?
Show solutionHide solution
A body cell has 46.
Meiosis halves it: 46 / 2 = 23.
23
Genetics: Mendel, DNA and inheritance
'Father of genetics', 'DNA double helix', 'Mendel worked on which plant', 'who decides the sex of a child'.
Match the name to its one fact.
Mendel is the garden pea. Watson and Crick is 1953.
Sex: the mother always gives X. The father gives X or Y.
One name, one organism and one year make up the whole question.
Watson and Crick are famous for which work?
Show solutionHide solution
Their year is 1953.
They built the model of DNA.
The double-helix model of DNA
Blood cells and cell records
'Which blood cells lack a nucleus', 'lifespan of RBC', 'largest / longest cell', 'which cell carries oxygen'.
RBC has no nucleus, carries oxygen and lives about 120 days.
WBC defends. Platelets clot the blood.
Records: ovum is the largest human cell. Nerve cell is the longest.
Each blood cell has one job.
What is the average lifespan of a human red blood cell?
Show solutionHide solution
RBCs live about 120 days.
The spleen removes worn-out RBCs.
About 120 days
Shortcuts that save time
These four nicknames answer most organelle questions.
Which organelle is called the 'suicide bag' of the cell?
Show solutionHide solution
Suicide points to self-digestion.
Lysosomes hold digestive enzymes.
Lysosome.
Hooke saw the cell (1665, dead cork). Leeuwenhoek saw it alive. Brown saw the nucleus. Schleiden and Schwann made the theory. Virchow said cells come from cells.
Mistakes to avoid
Where most students lose marks on this subtopic.
Saying Leeuwenhoek discovered the cell.
Hooke named the cell. Leeuwenhoek first saw living cells.
Saying the mother decides the child's sex.
The father decides it. His sperm carries X or Y.
Giving animal cells a cell wall.
Only plants, fungi and bacteria have one.
Thinking meiosis makes two identical cells.
Mitosis gives 2 identical cells. Meiosis gives 4 cells with half the chromosomes.
Saying every cell has a nucleus.
Prokaryotes have none. Mature mammalian RBCs have none.
Quick revision
Read this the night before the exam.
Hooke 1665 cork; Leeuwenhoek living cells; Brown nucleus 1831; Schleiden-Schwann theory; Virchow: cells from cells.
Mitochondria: powerhouse. Lysosome: suicide bag. Ribosome: protein. Golgi: packaging.
Cell wall: cellulose in plants, chitin in fungi. Absent in animal cells.
Largest cell: ostrich egg. Longest: neuron. Smallest: Mycoplasma.
Mitosis: 2 identical cells. Meiosis: gametes, chromosomes halved.
Human: 46 chromosomes (23 pairs). Gamete: 23. Father decides sex.
Mendel: pea. Watson and Crick: DNA 1953. Down syndrome: trisomy 21.
Practice: 18 questions
Sets of 10, mixed across the question types above. Every answer has a step-by-step explanation.
Topic test · 10 questions
Suggested time 3 min · wrong answers go to your mistake notebook automatically.